// Science · Glossary

Entourage Effect

⚗️ Science First mentioned: Ep. 001

The principle that cannabis works best as a complete plant profile. The 80+ cannabinoids and 300+ terpenes present in cannabis work synergistically. The healing effects attributed to any single compound like CBD or THC are almost certainly the product of all of them working together, not one acting alone.

Bubbleman used this concept as the backbone of his argument against CBD isolate legislation and single-compound thinking. He cited the example of a mother treating her three-year-old's brain tumour with CBD-only medicine while actively avoiding THC — the compound with the strongest tumour-reducing evidence behind it. The entourage effect suggests that isolating any one cannabinoid and crediting it with the full healing effect of cannabis is fundamentally missing the point.

Ep. 001 Where It All Began