// Science · Glossary

Endocannabinoid System

⚗️ Science First mentioned: Ep. 001

The body's internal regulatory network responsible for maintaining homeostasis. It produces its own cannabinoids from essential amino acids, particularly omega-3 and omega-6 fatty acids. Phytocannabinoids from cannabis interact with this system to extend and support its function.

Bubbleman explained that the endocannabinoid system maintains biological homeostasis — keeping the body in balance. The body produces its own cannabinoids from essential amino acids (omega-3s and omega-6s). Phytocannabinoids from cannabis support and extend that system. The point isn't about getting high — it's about keeping the body regulated. One guest was six days off 400mg of daily morphine, finding that cannabinoids gave better mobility than opioids, illustrating the practical medical significance of this system.

Ep. 001 Where It All Began